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(always used with a modifier) boredom resulting from overexposure to something; "he was suffering from museum fatigue"; "after watching TV with her husband she had a bad case of football fatigue"; "the American public is experiencing scandal fatigue"; "political fatigue"
temporary loss of strength and energy resulting from hard physical or mental work; "he was hospitalized for extreme fatigue"; "growing fatigue was apparent from the decline in the execution of their athletic skills"; "weariness overcame her after twelve hours and she fell asleep"