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n.
the choicest or most essential or most vital part of some idea or experience; "the gist of the prosecutor's argument"; "the heart and soul of the Republican Party"; "the nub of the story"
n.
the highest point of anything conceived of as growing or developing or unfolding; "the climax of the artist's career"; "in the flood tide of his success"
n.
an event marking a unique or important historical change of course or one on which important developments depend; "the agreement was a watershed in the history of both nations"
n.
a crisis situation or point in time when a critical decision must be made; "at that juncture he had no idea what to do"; "he must be made to realize that the company stands at a critical point"
n.
the subject matter of a conversation or discussion; "he didn't want to discuss that subject"; "it was a very sensitive topic"; "his letters were always on the theme of love"